Macao is a multicultural and multilingual area, which offers excellent brain research resources in language, translations and cognitive linguistics involved the Cantonese, Mandarin, Portuguese and English. The platform in CCBS can reveal the brain cognition mechanism associated with multilingualism and multilingual translation.

Macao is a multicultural and world’s entertainment capital, which offers excellent brain research resources for the study of addiction and decision making. The platform in CCBS can help reveal neural mechanism of addiction, and explore new methods of intervention and treating addictive behaviors.

Macao’s average life expectancy is ranked No. 2 in the world, which can result in issues related to cognitive aging and increased incidence of brain disorders. In addition, children’s brain development is essential for the future of Macao. CCBS’s brain plan should also focus on the study of children’s brain cognitive mechanism and behavior, promoting children’s brain development and personality shaping. Further, early prevention, early diagnosis, early treatment and intervention, and therapeutic evaluation methods development for brain disorders is one of the core topics of CCBS’s brain projects.

Neuroimaging techniques have changed the way neuroscientists address questions about functional anatomy, especially in relation to behavior and clinical disorders. Neuroimaging includes the use of various techniques to either directly or indirectly image the structure or function of the brain. The core facility in CCBS is the functional magnetic resonance imaging (fMRI) system. fMRI uses magnetic resonance imaging to measure the changes in hemodynamics including blood oxygen and blood flow induced by neuronal activity, which can be used to map the brain activation and brain networks in frequency-temporal-spatial domain in order to systematically study the neural mechanisms associated with brain cognition and brain disorders. In addition to 3T fMRI, the comprehensive research platform in CCBS also include other functional neuroimaging platforms such as electroencephalograph (EEG), functional near-infrared spectroscopy (fNIRS) or other fused multimodal neuroimaging techniques.